Medicine Research Writing Editing and Proofreading Services

The trial registration lists mortality at twelve months as the primary outcome. The published paper reports a composite of mortality, hospitalisation and symptom score, which is significant, and mentions the twelve-month mortality figure once, in a table, where it is not. Nothing in the paper is untrue. The reader who does not open the registry is being told a different study happened.

We edit what medical researchers write — trial reports and protocols, observational studies, systematic reviews and meta-analyses, case series and reports, statistical analysis plans, regulatory and ethics submissions, clinical guideline documents, and theses, articles and grant applications. Our editors work on the correspondence between what was planned and what is reported.

The relationship between the prespecified plan and the published paper is what makes a clinical finding trustworthy, and its failure is an outcome quietly changed between them. Selective reporting is rarely deliberate and is nearly always visible to anyone who checks. We work through these so the primary outcome in the paper is the primary outcome in the registration and the protocol, stated as such and reported whatever it showed; so any change is declared with its date, its reason and whether it preceded unblinding, since a documented amendment before data were seen is legitimate and an undocumented one afterwards is not; so secondary and exploratory outcomes are labelled as what they are and not promoted in the abstract when the primary is null; so subgroup analyses are identified as prespecified or post hoc, because a post hoc subgroup is hypothesis-generating however striking it looks; so the analysis population is defined and the handling of missing data described as planned rather than as chosen; so the abstract's conclusion matches the primary result, given that most readers read nothing else; and so harms are reported with the same care as benefits. Papers written this way survive the scrutiny of the people who compile the evidence.

Everything you send is treated in confidence, including unpublished trial data, protocols and regulatory correspondence. We are editors rather than clinicians, statisticians or regulatory professionals, and we offer no view on trial conduct, results or clinical practice. What we can do is keep the paper faithful to the plan.